Dr. Charmandari carries out her clinical work as a Professor of Pediatric and Adolescent Endocrinology, at the Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, "Aghia Sophia" Children's Hospital. She also participates regularly at the outpatient clinics of the Division of Endocrinology, Metabolism and Diabetes, at the Eugenides Medical Center.

Dr. Charmandari also consults patients with conditions related to Pediatric and Adolescent Endocrinology in her private clinic.